Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length118 amino acids

Chemical FormulaC604H947N159O168S6

DescriptionStandard

        PKTLPMAHESMLLLAVTEFVASLATSTYFTAGALHRNISSDMLPRQFLLQLRTKNMEVFSPELQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPVFLLNI
    

Molecular Weight13316.33 Da

Isoelectric Point (pI)6.21

Net Charge (pH 7.0)-1.60

Net Charge (pH 7.4) -1.94

Charge Density (pH 7.0) -0.0135

GRAVY Index0.10

Hydrophobic Moment 0.52

Boman Index0.13

Instability Index55.12

Aliphatic Index 99.24

Aromaticity 0.0847

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5145.82

LogP -42.58

H-bond Donors 176.0

H-bond Acceptors 177.0

Rotatable Bonds 425.0

Heavy Atoms 937.0

Ring Count 26.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363077 VERIFIED: NO

Provenance & Taxonomy

OrganismPomatostomus ruficeps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria