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MYP_048083
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Basic Information
TCTPPTD
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C57H93N15O15S
Standard
Sequence
MIIYRDLISH
Physicochemical Analysis
1260.50 Da
6.50
-0.41
-0.68
-0.0412
0.59
0.32
0.21
-7.91
156.00
0.1000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
493.56
-1.66
18.0
17.0
41.0
88.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161103 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
TCTP
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
RECORD: Rec_0214987 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
TCTP
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorophore labeling
Amidation
N-term detail: Rhodamine labeling
Bio-Activity Profile
Cell-penetrating peptide
HeLa
Fluorescence-based uptake assay
PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
RECORD: Rec_0218553 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23256924 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23256924/
RECORD: Rec_0263746 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine B
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. Eur J Pharm Sci. 2011 May 18;43(1-2):25-31. doi: 10.1016/j.ejps.2011.03.007. PMID: 21440624. PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
RECORD: Rec_0339282 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine B
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. Eur J Pharm Sci. 2011 May 18;43(1-2):25-31. doi: 10.1016/j.ejps.2011.03.007. PMID: 21440624. PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
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