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MYP_048038
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Basic Information
NP-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
32 amino acids
C158H261N59O41S6
Standard
Sequence
VTCYCRRTRCGFRERLSGACGYRGRIYRLCCR
Physicochemical Analysis
3835.52 Da
9.99
7.67
7.37
0.2398
-0.49
0.63
-0.41
20.14
48.75
0.1250
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1681.20
-19.58
73.0
55.0
126.0
264.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0290240 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35 [18 h
100
MIC
PMID2543629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2543629/
RECORD: Rec_0290361 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
128 μM
MIC
PMID29282543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29282543/
RECORD: Rec_0294821 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. pullorum C79-13
16 μM
MIC
PMID29282543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29282543/
RECORD: Rec_0359671 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-31, 5-20, 10-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ML-35 [18 h]
100 CFU/mL
MIC
PMID2543629;7594610 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2543629/
RECORD: Rec_0367498 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. pyocyaneum ATCC 27853
128 μM
MIC
PMID29282543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29282543/
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