Peptide Database

Peptide NameBeta-defensin-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC353H578N104O85S7

DescriptionStandard

        MRIHYLLFALLFLFLLPVPGNGGIISGLRKYYCKIRSGRCALIGCLPKEEEIGHCSLTGRKCCRRKKNH
    

Molecular Weight7863.47 Da

Isoelectric Point (pI)9.84

Net Charge (pH 7.0)9.70

Net Charge (pH 7.4) 9.23

Charge Density (pH 7.0) 0.1406

GRAVY Index0.07

Hydrophobic Moment 0.57

Boman Index0.01

Instability Index57.05

Aliphatic Index 103.19

Aromaticity 0.0870

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3030.90

LogP -22.46

H-bond Donors 115.0

H-bond Acceptors 105.0

Rotatable Bonds 265.0

Heavy Atoms 549.0

Ring Count 12.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255102 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence