Peptide Database

Peptide NameyrrL signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC184H298N44O42S

DescriptionStandard

        MYINQQKKSFFNKKRIILSSIVVLFLIIGGAFL
    

Molecular Weight3830.67 Da

Isoelectric Point (pI)10.58

Net Charge (pH 7.0)4.50

Net Charge (pH 7.4) 4.27

Charge Density (pH 7.0) 0.1362

GRAVY Index0.82

Hydrophobic Moment 0.40

Boman Index0.29

Instability Index47.75

Aliphatic Index 138.79

Aromaticity 0.1515

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1413.78

LogP -6.32

H-bond Donors 49.0

H-bond Acceptors 48.0

Rotatable Bonds 133.0

Heavy Atoms 271.0

Ring Count 5.0

Amide Bonds 36.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0105586 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

MethodSecretion phenotype assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/