Peptide Database

Peptide NameSyn-safencin-89

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC151H240N42O34

DescriptionStandard

        AWKETIRQYLKNEIKKKWRKAVIAW
    

Molecular Weight3187.78 Da

Isoelectric Point (pI)10.38

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.2318

GRAVY Index-0.97

Hydrophobic Moment 0.68

Boman Index-0.26

Instability Index15.20

Aliphatic Index 86.00

Aromaticity 0.1600

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1290.25

LogP -5.39

H-bond Donors 47.0

H-bond Acceptors 40.0

Rotatable Bonds 110.0

Heavy Atoms 227.0

Ring Count 7.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096005 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity1.05 μM

MethodIC50

RECORD: Rec_0407583 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50