Peptide Database

Peptide NameIFN-α17

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC853H1347N233O259S9

DescriptionStandard

        CDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFGLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKILRRKD
    

Molecular Weight19298.81 Da

Isoelectric Point (pI)5.46

Net Charge (pH 7.0)-3.98

Net Charge (pH 7.4) -4.44

Charge Density (pH 7.0) -0.0240

GRAVY Index-0.39

Hydrophobic Moment 0.76

Boman Index-0.05

Instability Index62.49

Aliphatic Index 86.39

Aromaticity 0.0904

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8037.35

LogP -80.94

H-bond Donors 279.0

H-bond Acceptors 267.0

Rotatable Bonds 657.0

Heavy Atoms 1354.0

Ring Count 25.0

Amide Bonds 186.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405553 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 1 and 99, and 29 and 139

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)