Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length345 amino acids

Chemical FormulaC1752H2731N429O497S15

DescriptionStandard

        VKTGKMLKFWYFFLLLHLLIQQLDANPGLKVRITQKGVRINTIEFPDVSISLIPGIGIKLSTQRAYATISMNWSIRTWLFKDSGSATVSISGVFITSVITMSQDSTGHPSMSLDSCQMSIRGVEVKLNGTIRYVARDFIYSSAGVLKLGVESCFVLSTTFTVPTQIDAFAQIDYSLVNSPGVFQSFIDLDLKGAIYPVGNWTDLAFVPAPFILPDKSDSMLYFGISEYFFKSASLAYYTSGAFNITMIEETLFLCLETLQIAKYYVEARPAMMHLRAAAPPVVSLQTDTFSLEICASMEVLAVLPDSTTQSIFTVNIVSTMDQRITFHLGVKISLFFHTARNQGI
    

Molecular Weight38236.98 Da

Isoelectric Point (pI)6.57

Net Charge (pH 7.0)-0.85

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0025

GRAVY Index0.37

Hydrophobic Moment 0.68

Boman Index0.22

Instability Index36.77

Aliphatic Index 102.00

Aromaticity 0.1159

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0415673 VERIFIED: NO

Provenance & Taxonomy

OrganismChelonoidis abingdonii (Abingdon island giant tortoise) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria