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MYP_047848
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Basic Information
Penilumamide D
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Cardiovascular
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
not Standard
3 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XAX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031063 VERIFIED: YES
Provenance & Taxonomy
Stagonospora trichophoricola,Aspergillus sp. [Fungus]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1,3
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Human colon adenocarcinoma HCT 116
PMID28676717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28676717/
RECORD: Rec_0039747 VERIFIED: YES
Provenance & Taxonomy
Stagonospora trichophoricola,Aspergillus sp. [Fungus]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1,3
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Pseudomonas putida
PMID28676717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28676717/
RECORD: Rec_0061752 VERIFIED: YES
Provenance & Taxonomy
Bothrops jararaca [Animal]; synthetic construct [Synthetic]
ACE inhibitor
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Ethyl-4-phenylbutanoyl
Non-standard residues/X at 1, 3
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive Cardiovascular
Human angiotensin-converting enzyme
Clinical/Human: The active metabolite quinaprilat has an elimination half life of 2.3 h
PaperQuinapril: a new second-generation ACE inhibitor PMID2068835 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2068835/
RECORD: Rec_0062738 VERIFIED: YES
Provenance & Taxonomy
Stagonospora trichophoricola,Aspergillus sp. [Fungus]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1,3
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Pseudomonas aeruginosa
PMID28676717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28676717/
RECORD: Rec_0081228 VERIFIED: YES
Provenance & Taxonomy
Stagonospora trichophoricola,Aspergillus sp. [Fungus]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1,3
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Staphylococcus epidermidis
PMID28676717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28676717/
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