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MYP_047769
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Basic Information
NPP
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
77 amino acids
C359H557N109O117S5
Standard
Sequence
WCLESSQCQDLTTESNLLACIRACKPDLSAETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNGSSSSGVGGAAQ
Physicochemical Analysis
8432.25 Da
5.70
-1.18
-1.50
-0.0153
-0.67
0.73
-0.11
62.08
53.25
0.0779
12490.00
12740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3658.08
-47.14
130.0
122.0
273.0
590.0
14.0
84.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060273 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
POMC
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Phe61 Amidation
Bio-Activity Profile
Hormone precursor Neuropeptide precursor
RECORD: Rec_0267045 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
NPP
9913
Structure & Mods
disulfide-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
2-24; 8-20
61:Phenylalanine amide; 45:O-linked (GalNAc...) threonine; 65:N-linked (GlcNAc...) asparagine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation
Mammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min