Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC483H781N127O132S9

DescriptionStandard

        MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPSHPKPATLALTLQDYVTIIENFPSL
    

Molecular Weight10767.72 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)3.61

Net Charge (pH 7.4) 3.16

Charge Density (pH 7.0) 0.0384

GRAVY Index-0.02

Hydrophobic Moment 0.71

Boman Index0.05

Instability Index41.42

Aliphatic Index 99.57

Aromaticity 0.0745

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4161.74

LogP -32.02

H-bond Donors 146.0

H-bond Acceptors 147.0

Rotatable Bonds 358.0

Heavy Atoms 751.0

Ring Count 16.0

Amide Bonds 103.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0051475 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence