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MYP_047676
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Basic Information
R2PLx
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C127H226N36O38S3
Standard
Sequence
GIMDTVKNAAKNLAGQLLDKLKCKITAC
Physicochemical Analysis
2961.57 Da
9.24
2.74
2.50
0.0978
0.12
0.64
0.03
3.78
108.21
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1223.45
-12.25
43.0
44.0
106.0
204.0
0.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0277915 VERIFIED: YES
Provenance & Taxonomy
Rana palustris [Animal]
Palustrin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antitumor Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus
256 μM
MIC
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0286811 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
U-251MG
16.14 μM
IC50
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0298883 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Horse erythrocytes: Moderate haemolytic activity
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0314594 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli(NCTC 10418)
32 μM
MIC
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0335182 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
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