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MYP_047676
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Basic Information
R2PLx
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C127H226N36O38S3
Standard
Sequence
GIMDTVKNAAKNLAGQLLDKLKCKITAC
Physicochemical Analysis
2961.57 Da
9.24
2.74
2.50
0.0978
0.12
0.64
0.03
3.78
108.21
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1223.45
-12.25
43.0
44.0
106.0
204.0
0.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0122816 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H157
5.9 μM
IC50
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0128001 VERIFIED: YES
Provenance & Taxonomy
Rana palustris [Animal]
Palustrin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antitumor Anti-Gram-positive Anti-Gram-negative
PC-3
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0141677 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa(ATCC 27853)
512 μM
MIC
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0147888 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0152555 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-435S
15.44 μM
IC50
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
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