Peptide Database

Peptide NameBeta-defensin 131A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC382H578N98O99S8

DescriptionStandard

        MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYYHCRLKCNADEHAIRYCADFSICCKLKIIEIHGQKKW
    

Molecular Weight8383.79 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0241

GRAVY Index0.10

Hydrophobic Moment 0.52

Boman Index0.08

Instability Index41.48

Aliphatic Index 82.39

Aromaticity 0.1549

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3146.15

LogP -20.78

H-bond Donors 116.0

H-bond Acceptors 112.0

Rotatable Bonds 271.0

Heavy Atoms 587.0

Ring Count 18.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093102 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KJ8/entry; https://bblserver.org.in/ampdb/