Peptide Database

Peptide NameTemporin-SHd (Temp-SHd) (Temporin-1Sd) (Temp-1Sd)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC255H410N68O85S

DescriptionStandard

        FLGTINLSLCEQERDADEEKRDEPDESDVEVEKRFLPAALAGIGGILGKLFGK
    

Molecular Weight5820.45 Da

Isoelectric Point (pI)4.39

Net Charge (pH 7.0)-6.23

Net Charge (pH 7.4) -6.47

Charge Density (pH 7.0) -0.1175

GRAVY Index-0.43

Hydrophobic Moment 0.47

Boman Index-0.05

Instability Index43.39

Aliphatic Index 92.08

Aromaticity 0.0566

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2480.49

LogP -22.98

H-bond Donors 84.0

H-bond Acceptors 80.0

Rotatable Bonds 202.0

Heavy Atoms 409.0

Ring Count 5.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050725 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-MRSA Anti-Gram-positive Cytolytic Hemolytic

TargetTrypanosoma

RECORD: Rec_0069616 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-MRSA Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0284555 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-MRSA Anti-Gram-positive Cytolytic Hemolytic

TargetLeishmania