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MYP_047646
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Basic Information
H8
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
40 amino acids
C191H290N58O54S6
Standard
Sequence
GFGCNGPWNEDDLRCRNRCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4455.09 Da
9.06
4.70
4.39
0.1174
-0.74
0.33
-0.16
14.51
29.25
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1843.11
-20.87
71.0
65.0
147.0
309.0
8.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0215725 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. pneumoniae CVCC2350
1.818 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0230293 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 6538
0.227 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0271911 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-typhimurium ATCC 14028
>7.273 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0286950 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. suis CVCC3928
0.057 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0356027 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. pneumoniae CVCC1.8722 or CVCC2350
1.818 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
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