Peptide Database

Peptide NameMotilin(1–12)ghrelin(16–28)

Function Ontology

Gastrointestinal bioactivity ▸ Gastrointestinal motility

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC138H221N37O35

DescriptionStandard

        FVPIFTYGELQRKESKKPPAKLQPR
    

Molecular Weight2958.46 Da

Isoelectric Point (pI)10.17

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1504

GRAVY Index-0.98

Hydrophobic Moment 0.39

Boman Index-0.23

Instability Index58.36

Aliphatic Index 62.40

Aromaticity 0.1200

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1175.91

LogP -8.39

H-bond Donors 39.0

H-bond Acceptors 39.0

Rotatable Bonds 96.0

Heavy Atoms 210.0

Ring Count 7.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106573 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyMotilin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Gastrointestinal motility

TargetGPR38 agonist activity

Activity0.01-0.009 μM

MethodEC50

Half-LifeIntravenouly injected in Sprague-Dawley rats, in vivo; 564 s