Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC601H947N153O174S6

DescriptionStandard

        YNLFSKFIDKALRKALEKQMCPLMAKSIADLNPRLKTLNVLAKVDKYAEIEYSMVSSPEISQPAMDLNLKGEFYNIGRHQEAPVPAPAFSLPAQSSNMIYIALSSYTPNSAGFVYKNAGV
    

Molecular Weight13292.26 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.54

Charge Density (pH 7.0) 0.0237

GRAVY Index-0.13

Hydrophobic Moment 0.85

Boman Index0.07

Instability Index56.76

Aliphatic Index 87.92

Aromaticity 0.1000

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5236.60

LogP -47.32

H-bond Donors 176.0

H-bond Acceptors 184.0

Rotatable Bonds 436.0

Heavy Atoms 934.0

Ring Count 22.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0355445 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias melastigma [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence