Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length482 amino acids

Chemical FormulaC2421H3840N628O688S15

DescriptionStandard

        MLKTWYFVLLCWLSLQLEANPGLKVRITQKGLDYGRRIGMELVKQAVLKETFPSWSGQESLSVVKVNYVISRLRINAVDFPETSASFIPGTGICLSVARASATISADWRMNAWLLKGKGEITVSISGLFISIIFNVSRDSTGHLSTLLHNCQLSIGSVKVKLSGRSSWIYSFLSGYLEKPIHTKLDKNLCLNIKYKIQMMDAQLKKHKVLSQIDTFAQVDYSLLSSPAVFKSHINLDLKGTVYPVGNHTDPPFMPAPFALPNQGDSMIYLGVSNYFLKSASLAYYRAGAFNITISEELATTFSLNTSLLKYFVSETSLSQAAACPVLLNLMATLPPAVSLNADRCVLQITGSVEVFAALPNSTTQYIFTGNLTASTTANLTITKQKLIISLLLKRFQFSLLHSNLGFPEQKSVVENFLSYALRRVVIPVINDKLGKGFPLLNLAHTSLTGPAIKMNQGHLVISTDVHYQPVDREDEDLHSHS
    

Molecular Weight53233.16 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)12.50

Net Charge (pH 7.4) 11.49

Charge Density (pH 7.0) 0.0259

GRAVY Index0.15

Hydrophobic Moment 0.72

Boman Index0.14

Instability Index32.02

Aliphatic Index 105.58

Aromaticity 0.0913

Extinction Coeff. Reduced 56840.00

Extinction Coeff. Oxidized 57215.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372603 VERIFIED: NO

Provenance & Taxonomy

OrganismLepidothrix coronata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria