Peptide Database

Peptide NameSLAY-screened peptide P3927

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC39H68N12O12S

DescriptionStandard

        AMNDRPLL
    

Molecular Weight929.10 Da

Isoelectric Point (pI)5.88

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.39

Charge Density (pH 7.0) -0.0254

GRAVY Index-0.23

Hydrophobic Moment 0.17

Boman Index-0.09

Instability Index23.40

Aliphatic Index 110.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 400.52

LogP -3.22

H-bond Donors 13.0

H-bond Acceptors 13.0

Rotatable Bonds 29.0

Heavy Atoms 64.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0274831 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/