Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC429H649N109O126S9

DescriptionStandard

        MKTFSVAAALAVMLTFIYIQESSAVPVSEEQVLEEPVSPEHPAAAHEETTVDSWKMLYNSRNKPGIHCHFCYGCYTSGLCKFCCRF
    

Molecular Weight9637.98 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-3.19

Net Charge (pH 7.4) -3.73

Charge Density (pH 7.0) -0.0371

GRAVY Index0.03

Hydrophobic Moment 0.51

Boman Index0.13

Instability Index61.47

Aliphatic Index 69.19

Aromaticity 0.1163

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3703.23

LogP -33.86

H-bond Donors 133.0

H-bond Acceptors 136.0

Rotatable Bonds 305.0

Heavy Atoms 673.0

Ring Count 20.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163514 VERIFIED: NO

Provenance & Taxonomy

OrganismAcanthochromis polyacanthus [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal