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MYP_047575
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Basic Information
Pleurain-D1 (Frogs,amphibians,animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Standard
23 amino acids
C117H197N27O27S2
Standard
Sequence
FLSGILKLAFKIPSVLCAVLKNC
Physicochemical Analysis
2478.11 Da
9.39
2.74
2.50
0.1190
1.38
0.56
0.41
-1.18
152.61
0.0870
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
856.34
-3.53
31.0
32.0
82.0
173.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184212 VERIFIED: YES
Provenance & Taxonomy
Nidirana pleuraden [Animal]
Pleurain
369511
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
17-23
Bio-Activity Profile
Antimicrobial Antibacterial
PaperX. Wang et al. / Peptides 28 (2007) 2069-2074. A new family of antimicrobial peptides from skin secretions of Rana pleuraden Evidence URLhttps://www.uniprot.org/uniprotkb/B5L1C2/entry
RECORD: Rec_0206217 VERIFIED: YES
Provenance & Taxonomy
Rana pleuraden [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
25 μg/mL
MIC
PMID19028675 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19028675/
RECORD: Rec_0222433 VERIFIED: YES
Provenance & Taxonomy
Nidirana pleuraden [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Yeast: Candida albicans
25 μg/mL
MIC
PMID19028675 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19028675/
RECORD: Rec_0237042 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative Antioxidant
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0249460 VERIFIED: YES
Provenance & Taxonomy
Nidirana pleuraden [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
50 μg/mL
MIC
PMID19028675 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19028675/
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