Peptide Database

Peptide NamePancreatic polypeptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC190H292N52O58S

DescriptionStandard

        YPPKPESPGEDASPEEMNKYLTALRHYINLVTRQRY
    

Molecular Weight4264.73 Da

Isoelectric Point (pI)6.77

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0041

GRAVY Index-1.21

Hydrophobic Moment 0.71

Boman Index-0.22

Instability Index98.51

Aliphatic Index 56.94

Aromaticity 0.1111

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1781.90

LogP -16.33

H-bond Donors 60.0

H-bond Acceptors 60.0

Rotatable Bonds 133.0

Heavy Atoms 301.0

Ring Count 10.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425428 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetNocardia brasiliensis

Activity20 μg/mL

MethodMIC

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