Peptide Database

Peptide NamePro-P18

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC149H232N36O35

DescriptionStandard

        EEEEAAAGKWKLFKKLPKFLHLAKKF
    

Molecular Weight3087.66 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.69

Charge Density (pH 7.0) 0.1125

GRAVY Index-0.64

Hydrophobic Moment 0.79

Boman Index-0.08

Instability Index39.06

Aliphatic Index 75.38

Aromaticity 0.1538

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1157.84

LogP -3.30

H-bond Donors 39.0

H-bond Acceptors 39.0

Rotatable Bonds 108.0

Heavy Atoms 220.0

Ring Count 7.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013163 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Other Modsamino acids, C:terminal = NH2, N:terminal = Ac

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli ATCC 25922

Activity82 μM

MethodMIC

RECORD: Rec_0114343 VERIFIED: YES