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MYP_047522
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Basic Information
Tryptophan-rich peptide PAF42
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
7 amino acids
C60H77N15O8
Standard
Sequence
WRKKWFW
Physicochemical Analysis
1136.35 Da
11.17
2.76
2.55
0.3940
-1.74
0.17
-0.27
8.57
0.00
0.5714
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
399.23
2.24
16.0
11.0
33.0
83.0
7.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0269041 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Hemolytic
human red blood cells
1 % hemolysis at 100 μM
Hemolysis
PMID17222805 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17222805/
RECORD: Rec_0289326 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Penicillium digitatum PHI-26
1.6 μM
IC50
PMID17222805 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17222805/
RECORD: Rec_0298119 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Aspergillus nidulans biA1
2.6 μM
IC50
PMID17222805 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17222805/
RECORD: Rec_0312661 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Alternaria sp. PHI-44
8 μM
MIC
PaperAntimicrobial properties of derivatives of the cationic tryptophan-rich hexapeptide PAF26 PMID17222805 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17222805/
RECORD: Rec_0318259 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli DH5alpha
8 μM
MIC
PMID17222805 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17222805/
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