Peptide Database

Peptide NameBeta-defensin 109

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC454H727N123O113S9

DescriptionStandard

        MRLHVLFFMLLFLTLLSPVRSGLASGENHCLNLSGVCRRDICKMTEDQIGACKRRWVCCRAWWILIPIPTPLIYSDYQEPLKPKLK
    

Molecular Weight10004.97 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0653

GRAVY Index0.19

Hydrophobic Moment 0.58

Boman Index0.08

Instability Index59.88

Aliphatic Index 107.67

Aromaticity 0.0930

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3750.67

LogP -23.77

H-bond Donors 138.0

H-bond Acceptors 130.0

Rotatable Bonds 325.0

Heavy Atoms 699.0

Ring Count 19.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116775 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal