Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length361 amino acids

Chemical FormulaC1816H2821N445O526S19

DescriptionStandard

        MQLVIFFLMILTHTYADYPALKAVLSEKGLRDVSQMMAVWIQNKLKSTEFPEVRGGVDIGIGTVNYVISNMQVVQCSMSGQSMEFKQGTGVSVEVSQLSLAITGSWATQFGIIHDGGSFDLAVYNININTLLGLGDEAGRLSITTISCSDDIGGVHIQFHGGASFFFEPFVSTFQGKISEMIHVRICPAIQQAISKLEMNLQKMPVSIPVNQYIYLSILFTSSPAVTDRSIELDIKGEFYSKSFPSEPPFSASAFDIKYAENYMLSLAASEFFVNSAAYAYLSSEVLQINITDNMIPKSFPFHLNTSQFGVFIPQVSMLCVQVMILEVKIDPVNLHKDASVLKHSLFVLNTLVQSYCYKLL
    

Molecular Weight39912.72 Da

Isoelectric Point (pI)5.34

Net Charge (pH 7.0)-8.82

Net Charge (pH 7.4) -9.59

Charge Density (pH 7.0) -0.0244

GRAVY Index0.31

Hydrophobic Moment 0.70

Boman Index0.22

Instability Index43.81

Aliphatic Index 100.94

Aromaticity 0.1080

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174830 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria