Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2314H3637N619O638S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIAVLEKELAQLKLPDISGDFRLRHVAKVHYEISRLDLRSFHLPYSRISLVPNVGLQVSISNAFAEVDGNWRVKMYFIRDHGSFDLKVENIYIKINLKLGSDASGKPTIDTSDCSTRISKVRVHFSGKFGWLYNLFRSAIESRFRKILESKVCENVVSSVRNELQPYLRTLPVTARIDAMTGIDYSLVAPPTATAQSLDVDLKGEFFSLAHRSAVPFPPLALAFPPDHNHMVYFGASSYFFNTAGFAYHAAGALVFEITDSTIPKGIDFHLNTTTFSAFIPQLEKMYPDMLMKLRLSAPSAPFLNIGPGGLSLKPVVDIQAYAILPNSSLAPLFLLSLVSNVSAVIDVKSGRIVGSLKVGRMKLSLKHSDVGTFQVRTLQSIMNIFASSILLPRLNARLDQGFPLPLPDRIQLSNILVRFHQNFLLLGADVHYQPR
    

Molecular Weight50657.04 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)11.62

Net Charge (pH 7.4) 10.61

Charge Density (pH 7.0) 0.0255

GRAVY Index0.10

Hydrophobic Moment 0.67

Boman Index0.11

Instability Index36.99

Aliphatic Index 103.27

Aromaticity 0.0987

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255773 VERIFIED: NO

Provenance & Taxonomy

OrganismThalassarche chlororhynchos (Atlantic yellow-nosed albatross) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria