Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC929H1413N209O288S8

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFQPFIDLDLKGVIFPAGNYTDSPYMAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNKTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEVPIISLQQDSFTVEIQGSMEVLVVLPDSTTQSLFTLNIAANSSISLNIFDQKLMGSLCLNR
    

Molecular Weight20373.90 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.24

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0774

GRAVY Index0.26

Hydrophobic Moment 0.55

Boman Index0.23

Instability Index55.19

Aliphatic Index 94.35

Aromaticity 0.1304

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7901.83

LogP -87.58

H-bond Donors 268.0

H-bond Acceptors 282.0

Rotatable Bonds 654.0

Heavy Atoms 1434.0

Ring Count 34.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027601 VERIFIED: NO

Provenance & Taxonomy

OrganismRegulus satrapa [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria