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MYP_047439
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C48H64N10O12
Standard
Sequence
YQKFPQY
Physicochemical Analysis
973.08 Da
8.50
0.76
0.55
0.1082
-1.76
0.52
-0.20
52.83
0.00
0.4286
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
381.79
-1.39
12.0
13.0
28.0
70.0
4.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153926 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
20.08 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0170206 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal] [Animal]; Capra hircus [Animal] [Animal]; Bos mutus grunniens [Animal]
Casein-derived peptide
9913;9925
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Antioxidant ACE inhibitory
Angiotensin-I converting enzyme
95.46 ± 0.18 μM
IC50
RECORD: Rec_0230945 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
alpha-S2-Casein-derived
9925
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
98.1 μM
IC50
PaperBioactive Peptides in Ovine and Caprine Cheeselike Systems Prepared with Proteases from Cynara cardunculus | Silva, SV. et al. | DOI: 10.3168/jds.S0022-0302(06)72370-0 Evidence URLhttps://www.uniprot.org/uniprotkb/P33049/entry
RECORD: Rec_0248208 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
alpha-S2-Casein-derived
9925
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
20.08 μM
IC50
PaperResistance of casein-derived bioactive peptides to simulated gastrointestinal digestion | Contreras, M. del Mar. et al. | DOI: 10.1016/j.idairyj.2013.05.008 Evidence URLhttps://www.uniprot.org/uniprotkb/P33049/entry
RECORD: Rec_0296885 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
alpha-S2-Casein-derived
9925
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
Spontaneously hypertensive rats
PaperResistance of casein-derived bioactive peptides to simulated gastrointestinal digestion | Contreras, M. del Mar. et al. | DOI: 10.1016/j.idairyj.2013.05.008 Evidence URLhttps://www.uniprot.org/uniprotkb/P33049/entry
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