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MYP_047409
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Basic Information
Cupiennin-1a [F2,6A]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
35 amino acids
C164H281N47O44S
Standard
Sequence
GAGALAKFLAKKVAKTVAKQAAKQGAKYVVNKQME
Physicochemical Analysis
3647.34 Da
10.30
6.76
6.54
0.1931
-0.19
0.69
-0.02
27.04
81.14
0.0571
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1511.00
-14.44
51.0
52.0
131.0
256.0
2.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0082714 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
>40 μM
HC50
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0190601 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cytolytic
Human erythrocytes
40 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/23523532/ PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0208206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
20-40 μM
MIC
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0248413 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis
0.625-1.25 μM
MIC
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0288743 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Paracoccus denitrificans
2.5-5 μM
MIC
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
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