Peptide Database

Peptide NamePutative antimicrobial peptide clone 4 (Non-disulfide-bridged peptide 4.23-like) (NDBP-4.23-like)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC386H620N102O100S4

DescriptionStandard

        MQMKYLIPIFFLVLIVADHCHAFLGMIPGLIGGLISAFKGRRKRDITSQIEQYRNLQKREAELEDILANLPVY
    

Molecular Weight8417.93 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)1.67

Net Charge (pH 7.4) 1.32

Charge Density (pH 7.0) 0.0229

GRAVY Index0.23

Hydrophobic Moment 0.51

Boman Index0.13

Instability Index49.05

Aliphatic Index 120.27

Aromaticity 0.0959

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3244.11

LogP -19.25

H-bond Donors 112.0

H-bond Acceptors 108.0

Rotatable Bonds 284.0

Heavy Atoms 592.0

Ring Count 12.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051794 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus costatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Anticancer Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0054109 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus costatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Anticancer Hemolytic

TargetCryptococcus neoformans

RECORD: Rec_0234119 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus costatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Anticancer Hemolytic

TargetCandida albicans

RECORD: Rec_0276656 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus costatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Anticancer Hemolytic

TargetCandida spp.

RECORD: Rec_0319965 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus costatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Antibiofilm Anti-Candida Anti-Gram-positive Anticancer Hemolytic

TargetEnterococcus faecalis