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MYP_047355
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Basic Information
Dermaseptin-3
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
30 amino acids
C139H236N38O40S
Standard
Sequence
ALWKTIIKGAGKMIGSLAKNLLGSQAQPES
Physicochemical Analysis
3111.66 Da
10.00
2.79
2.60
0.0932
0.03
0.66
0.15
42.16
104.33
0.0333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1265.79
-12.49
43.0
44.0
108.0
218.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0100188 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antitumor
PaperMedicinal Chemistry of ATP Synthase: A Potential Drug Target of Dietary Polyphenols and Amphibian Antimicrobial Peptides PMID20586714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20586714/
RECORD: Rec_0114666 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50.0 μM
MIC
PaperY. Fleury et al. / Biochimica et Biophysica Acta 1396 (1998) 228-236. Synthesis, antimicrobial activity and gene structure of a novel member of the dermaseptin B family Evidence URLhttps://www.uniprot.org/uniprotkb/P81488/entry
RECORD: Rec_0118390 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
gracilicutes
6.25
MIC
PMID9540838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9540838/
RECORD: Rec_0135482 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
C. glutamicum ATCC 13022
3.1 μM
MIC
PaperSynthesis, Antimicrobial Activity and Gene Structure of a Novel Member of the Dermaseptin B Family
RECORD: Rec_0160936 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Inactive
>100 μM
MIC
PaperSynthesis, Antimicrobial Activity and Gene Structure of a Novel Member of the Dermaseptin B Family
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