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MYP_047355
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Basic Information
Dermaseptin-3
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
30 amino acids
C139H236N38O40S
Standard
Sequence
ALWKTIIKGAGKMIGSLAKNLLGSQAQPES
Physicochemical Analysis
3111.66 Da
10.00
2.79
2.60
0.0932
0.03
0.66
0.15
42.16
104.33
0.0333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1265.79
-12.49
43.0
44.0
108.0
218.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000045 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
firmicutes
6.25
MIC
PMID9540838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9540838/
RECORD: Rec_0027885 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. citri R8A2
12.5 μM
MIC
PaperSynthesis, Antimicrobial Activity and Gene Structure of a Novel Member of the Dermaseptin B Family
RECORD: Rec_0051434 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0063445 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
A. laidlawii A-PG8
6.25 μM
MIC
PaperSynthesis, Antimicrobial Activity and Gene Structure of a Novel Member of the Dermaseptin B Family
RECORD: Rec_0065790 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. apis B31
6.25 μM
MIC
PaperSynthesis, Antimicrobial Activity and Gene Structure of a Novel Member of the Dermaseptin B Family
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