Peptide Database

Peptide NameCorticostatin-3 (Antiadrenocorticotropin peptide III) (Corticostatin III) (CS-III) (Macrophage antibiotic peptide MCP-1) (NP-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC450H756N142O130S7

DescriptionStandard

        MRTLALLAAILLVALQAQAEHVSVSIDEVVDQQPPQAEDQDVAIYVKEHESSALEALGVKAGVVCACRRALCLPRERRAGFCRIRGRIHPLCCRR
    

Molecular Weight10460.15 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.72

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.0181

GRAVY Index0.12

Hydrophobic Moment 0.60

Boman Index-0.03

Instability Index53.08

Aliphatic Index 110.95

Aromaticity 0.0211

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4372.76

LogP -42.43

H-bond Donors 159.0

H-bond Acceptors 142.0

Rotatable Bonds 350.0

Heavy Atoms 729.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0387991 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Non-hemolytic

TargetNo Target Organism Found

RECORD: Rec_0425708 VERIFIED: NO