Peptide Database

Peptide NameACE inhibitory peptide

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC23H35N7O11S

DescriptionStandard

        MHTDD
    

Molecular Weight617.63 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-2.41

Net Charge (pH 7.4) -2.68

Charge Density (pH 7.0) -0.4814

GRAVY Index-1.80

Hydrophobic Moment 0.08

Boman Index-0.32

Instability Index107.48

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 303.23

LogP -3.61

H-bond Donors 10.0

H-bond Acceptors 11.0

Rotatable Bonds 19.0

Heavy Atoms 42.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0190827 VERIFIED: YES

Provenance & Taxonomy

OrganismPrunus dulcis [Plant]; Prunus amygdalus [Plant]

FamilyACE inhibitory peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme

Activity67.52 μg/mL

MethodIC50

RECORD: Rec_0246649 VERIFIED: YES

Provenance & Taxonomy

OrganismPrunus armeniaca [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity67.52±0.05 μg/mL

MethodIC50