Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC587H954N168O182S8

DescriptionStandard

        MKLLLLALPILVLLPQVIPAYGGEKKCWNRSGHCRKQCKDGEAVKETCKNLRACCVPSNEDHRRLPTTSPTPLSDSTPGIIDNILTIRFTTDYFEISSKKDMVEGSEAGQGTQTSPPNVHHTS
    

Molecular Weight13533.39 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0147

GRAVY Index-0.44

Hydrophobic Moment 0.64

Boman Index-0.06

Instability Index55.82

Aliphatic Index 78.46

Aromaticity 0.0407

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5599.71

LogP -63.18

H-bond Donors 197.0

H-bond Acceptors 196.0

Rotatable Bonds 445.0

Heavy Atoms 945.0

Ring Count 20.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283425 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic