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MYP_047250
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Basic Information
LfcinB
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C80H125N27O14S2
Standard
Sequence
FKCRRWQWRMKK
Physicochemical Analysis
1753.15 Da
11.74
5.75
5.53
0.4789
-1.94
0.51
-0.77
92.11
0.00
0.2500
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
721.85
-3.45
29.0
22.0
60.0
123.0
5.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0065690 VERIFIED: YES
Provenance & Taxonomy
Bovine lactoferrin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
U266B1
55 μM
IC50
PaperPubMed PMID: 19527490 PMID19527490 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19527490/
RECORD: Rec_0067510 VERIFIED: YES
Provenance & Taxonomy
Bovine lactoferrin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 19527490 PMID19527490 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19527490/
RECORD: Rec_0068177 VERIFIED: YES
Provenance & Taxonomy
Bovine lactoferrin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Raji
13 μM
IC50
PaperPubMed PMID: 19527490 PMID19527490 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19527490/
RECORD: Rec_0082941 VERIFIED: YES
Provenance & Taxonomy
Bovine lactoferrin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
148±8 μM
IC50
PaperPubMed PMID: 19527490 PMID19527490 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19527490/
RECORD: Rec_0091414 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID19527490 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19527490/
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