Peptide Database

Peptide NameL-amino-acid oxidase (BjarLAAO-I; LAAO; LAO; snakes, reptils, animals)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC186H294N52O63S

DescriptionStandard

        ADDKNPLEECFRETDYEEFLEIARNGLKATSNPKRVV
    

Molecular Weight4298.70 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-3.20

Net Charge (pH 7.4) -3.42

Charge Density (pH 7.0) -0.0864

GRAVY Index-0.99

Hydrophobic Moment 0.69

Boman Index-0.26

Instability Index42.04

Aliphatic Index 65.95

Aromaticity 0.0811

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1902.99

LogP -19.42

H-bond Donors 65.0

H-bond Acceptors 61.0

Rotatable Bonds 145.0

Heavy Atoms 302.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108299 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararaca [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Antiparasitic Anticancer

RECORD: Rec_0134327 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0241398 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararaca [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-positive Oxidoreductase Cytolytic Toxin Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0303510 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararaca [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Antiparasitic Anticancer

TargetStaphylococcus aureus