Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length198 amino acids

Chemical FormulaC1009H1522N226O307S9

DescriptionStandard

        QIDDLAEVDYSLSSLPAIFRPFIDLDLKGIVFPAGNYTDSPYVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEESGNSFVFSLFFFLQTCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNVFDQKLMGSLCLNR
    

Molecular Weight22018.79 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.23

Net Charge (pH 7.4) -15.51

Charge Density (pH 7.0) -0.0769

GRAVY Index0.32

Hydrophobic Moment 0.62

Boman Index0.25

Instability Index42.46

Aliphatic Index 91.62

Aromaticity 0.1414

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8457.17

LogP -101.87

H-bond Donors 287.0

H-bond Acceptors 301.0

Rotatable Bonds 703.0

Heavy Atoms 1551.0

Ring Count 39.0

Amide Bonds 215.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022068 VERIFIED: NO

Provenance & Taxonomy

OrganismAphelocoma coerulescens (Florida scrub-jay) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria