Peptide Database

Peptide NameCalcitonin receptor-stimulating peptide 1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC227H359N71O60S5

DescriptionStandard

        ACNTATCMTHRLAGWLSRSGSMVRSNLLPTKMGFKIFNGPRRNSWF
    

Molecular Weight5203.04 Da

Isoelectric Point (pI)11.84

Net Charge (pH 7.0)6.86

Net Charge (pH 7.4) 6.59

Charge Density (pH 7.0) 0.1492

GRAVY Index-0.27

Hydrophobic Moment 0.60

Boman Index-0.04

Instability Index69.00

Aliphatic Index 55.22

Aromaticity 0.1087

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2131.47

LogP -24.48

H-bond Donors 80.0

H-bond Acceptors 73.0

Rotatable Bonds 168.0

Heavy Atoms 363.0

Ring Count 10.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232799 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCalcitonin

Tax ID9913

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-7

Bio-Activity Profile

Function

Hormone Calcium-regulatory peptide

RECORD: Rec_0327366 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0333496 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCalcitonin receptor-stimulating peptide

Tax ID9913

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-7

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

Targetporcine kidney cell

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour