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MYP_047124
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Basic Information
Kn2-5R-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
13 amino acids
C81H140N28O14
Standard
Sequence
FIRRIARLLRRIF
Physicochemical Analysis
1730.16 Da
12.00
4.76
4.56
0.3662
0.46
1.24
-0.26
112.17
157.69
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
722.02
-2.73
29.0
19.0
59.0
123.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella sp. clinical isolate 18
8 μM
MIC
PMID34361810 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34361810/
RECORD: Rec_0082711 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Toxicity
erythrocytes (hemolysis assay)
886.50 μM
HC50
PaperFine-Tuning of Alkaline Residues on the Hydrophilic Face Provides a Non-toxic Cationic alpha-Helical Antimicrobial Peptide Against Antibiotic-Resistant ESKAPE Pathogens. PMID34335511 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34335511/
RECORD: Rec_0088300 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
10 μg/mL
MIC
PMID34335511 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34335511/
RECORD: Rec_0113136 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-amino acids
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella sp. clinical isolate 55
4 μM
MIC
PMID34361810 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34361810/
RECORD: Rec_0114115 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC29213
5 μg/mL
MIC
PMID34335511 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34335511/
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