Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC840H1340N252O250S12

DescriptionStandard

        MGNRAKLSAAMLALIAAGVSAPTLMNQFLDEKEGNSLTAYRDGSQGIWTICRGATRIDGKPVTQGMKLTQAKCDQVNAIERDKALAWVDRNIHVPLTPPQKVGIASFCPYNIGPGKCFPSTFYQRINAGDRKGACEAIRWWIKDGGKDCRVRSNNCYGQVTRRDQESALTCWGIDQ
    

Molecular Weight19353.94 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.10

Charge Density (pH 7.0) 0.0427

GRAVY Index-0.41

Hydrophobic Moment 0.75

Boman Index-0.06

Instability Index30.18

Aliphatic Index 72.16

Aromaticity 0.0739

Extinction Coeff. Reduced 33460.00

Extinction Coeff. Oxidized 33960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8144.62

LogP -91.63

H-bond Donors 290.0

H-bond Acceptors 271.0

Rotatable Bonds 642.0

Heavy Atoms 1354.0

Ring Count 27.0

Amide Bonds 194.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0187794 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyLysozyme

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0302771 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella oxytoca [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic