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MYP_047061
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Basic Information
Myotoxin II (105-117)[Y3,6W][Y5K,P9W,C11A], PEM-2 [W5K,A9W]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C90H143N25O14
Standard
Sequence
KKWRKWLKWLAKK
Physicochemical Analysis
1799.26 Da
11.43
6.75
6.54
0.5195
-1.63
0.71
-0.49
21.68
67.69
0.2308
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
677.91
0.54
26.0
21.0
63.0
129.0
6.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0113953 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30447380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447380/
RECORD: Rec_0150759 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae ST258
4 μM
MIC
PMID30447380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447380/
RECORD: Rec_0153580 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30447380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447380/
RECORD: Rec_0223125 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30447380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447380/
RECORD: Rec_0250928 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ATCC 25922
2 μM
MIC
PMID30447380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30447380/
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