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MYP_047000
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Tripeptidyl Peptidase II Inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C17H31N3O4
Standard
Sequence
IPI
Physicochemical Analysis
341.45 Da
5.53
-0.24
-0.44
-0.0800
2.47
0.12
0.96
-2.93
260.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
112.73
0.97
3.0
4.0
8.0
24.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022324 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0031189 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV Inhibitory
Dipeptidyl peptidase IV
7.4
IC50
PaperMaruyama S., Ohmori T., Nakagami T.. Prolylendopeptidase inhibitory activity of a glial fibrillary acidic protein fragment and other proline-rich peptides. Biosci. Biotech. Biochem., 60, 358-359 (1996).
RECORD: Rec_0126001 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
IC50
PaperInvestigation into the bioavailability of milk protein-derived peptides with dipeptidyl-peptidase IV inhibitory activity using Caco-2 cell monolayers | Lacroix, IME. et al. | DOI: 10.1039/c6fo01411a Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0130609 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
3.5 μM
IC50
PaperInhibition of dipeptidyl peptidase IV (DPP-IV) by proline containing casein-derived peptides | Nongonierma, A. et al. | DOI: 10.1016/j.jff.2013.09.012 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0133031 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
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