Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC319H528N84O92S2

DescriptionStandard

        SPQICEITTHSVSSKLQPYLQTLPVTTKIDKVAWIDYSLVAPLRVTAENLDGQMKVRLVPRII
    

Molecular Weight7076.24 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.0245

GRAVY Index0.09

Hydrophobic Moment 0.61

Boman Index0.08

Instability Index44.05

Aliphatic Index 117.46

Aromaticity 0.0476

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2822.76

LogP -24.22

H-bond Donors 98.0

H-bond Acceptors 97.0

Rotatable Bonds 230.0

Heavy Atoms 497.0

Ring Count 10.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0260154 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus asinus asinus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence