Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 23.3

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC150H254N50O46S9

DescriptionStandard

        TKCSGSPECVKFCRTKGCRNGKCMNRSCKCYLCS
    

Molecular Weight3782.51 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)6.32

Net Charge (pH 7.4) 6.00

Charge Density (pH 7.0) 0.1858

GRAVY Index-0.57

Hydrophobic Moment 0.68

Boman Index-0.30

Instability Index63.91

Aliphatic Index 20.00

Aromaticity 0.0588

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1595.72

LogP -23.34

H-bond Donors 66.0

H-bond Acceptors 62.0

Rotatable Bonds 129.0

Heavy Atoms 255.0

Ring Count 3.0

Amide Bonds 35.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0030192 VERIFIED: NO

Provenance & Taxonomy

OrganismScorpiops tibetaus [Animal]

Structure & Mods

Configdisulfide-stabilized linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-23; 9-28; 13-30; 18-33

Bio-Activity Profile

Function

Toxin Ion channel blocker

TargetKv1.3/KCNA3