Peptide Database

Peptide NameBeta-defensin 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC207H335N73O50S6

DescriptionStandard

        QGVRNHVTCRIYGGFCVPIRCPGRTRQIGTCFGRPVKCCRRW
    

Molecular Weight4838.72 Da

Isoelectric Point (pI)10.74

Net Charge (pH 7.0)8.79

Net Charge (pH 7.4) 8.44

Charge Density (pH 7.0) 0.2092

GRAVY Index-0.34

Hydrophobic Moment 0.76

Boman Index-0.19

Instability Index57.30

Aliphatic Index 55.48

Aromaticity 0.0952

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2005.93

LogP -22.17

H-bond Donors 80.0

H-bond Acceptors 66.0

Rotatable Bonds 153.0

Heavy Atoms 336.0

Ring Count 9.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372563 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-31; 16-38; 21-39

Bio-Activity Profile

Function

Antimicrobial

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