‹ ›
MYP_046906
← PREVIOUS NEXT → BACK
Basic Information
Kasseptin 1Mb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C97H154N24O23
Standard
Sequence
FFGAIAAALPHVISAIKNAL
Physicochemical Analysis
2024.41 Da
8.76
0.85
0.59
0.0423
1.42
0.51
0.56
10.64
142.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
725.45
-3.80
24.0
25.0
62.0
144.0
4.0
20.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0016312 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
16 μM
Hemolysis
PMID19427345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19427345/
RECORD: Rec_0041293 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Kasseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
120.0 μM
HC50
PaperL. Wang et al. / Peptides 30 (2009) 1428-1433. A family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata Evidence URLhttps://www.uniprot.org/uniprotkb/C7C1K9/entry
RECORD: Rec_0114570 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
16 μM
MIC
PMID19427345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19427345/
RECORD: Rec_0153949 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-positive Cytotoxic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0181055 VERIFIED: YES
Provenance & Taxonomy
Kassina maculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
At the same concentration, the peptide can cause hemolysis (horse blood) by ~50%
PaperA family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata.
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4