Peptide Database

Peptide NameRibonuclease 7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Standard StatusStandard

Sequence Length129 amino acids

Chemical FormulaC637H1024N192O181S13

DescriptionStandard

        MKPKGMTSSQWFKIQHMQPSPQACNSAMKNINKHTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCRYKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL
    

Molecular Weight14684.97 Da

Isoelectric Point (pI)9.80

Net Charge (pH 7.0)16.02

Net Charge (pH 7.4) 15.30

Charge Density (pH 7.0) 0.1242

GRAVY Index-0.85

Hydrophobic Moment 0.69

Boman Index-0.19

Instability Index55.82

Aliphatic Index 50.62

Aromaticity 0.0620

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6056.98

LogP -70.04

H-bond Donors 211.0

H-bond Acceptors 217.0

Rotatable Bonds 493.0

Heavy Atoms 1023.0

Ring Count 26.0

Amide Bonds 146.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076399 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familypancreatic ribonuclease family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide23-81; 37-91; 55-106; 62-69

Bio-Activity Profile

Function

Antimicrobial pancreatic ribonuclease family Antibacterial Host defense